The Shvabe holding of the Rostec State Corporation is creating a gas-liquid artificial lung ventilation (GZhIVL), which will save the lives of premature babies with insufficient opening of the lungs. The layout of the device has passed preliminary tests, preparations are underway for its experimental testing.
“This method will be used in medicine to provide care in critical conditions, both in adults and newborns, for the treatment of severe bronchopulmonary diseases, as well as for the rapid cooling of the human body during emergency brain surgery,” said the Deputy General Director of the Fund for Advanced research Vitaly Davydov.
One of the main causes of death in premature infants is bronchopulmonary dysplasia, which occurs when the lungs do not open sufficiently. The therapy involves the use of liquid breathing technology. It lies in the fact that the lungs are filled with a mixture saturated with dissolved oxygen, which penetrates into the blood. Liquid breathing is used for a mild form of lung development in newborns and to prepare them for spontaneous breathing.
At the moment, Shvabe specialists are carrying out work to modernize the GZhIVL experimental device for adults already created at the first stage of the project by installing a new desaturation module on it, which allows you to effectively and safely remove carbon dioxide dissolved in the respiratory fluid and saturate it with oxygen. After that, the experimental testing of the GZhIVL device will take place and the registration of the product will begin.
“The economic effect of its introduction into clinical practice will be that doctors will be able to perform artificial lung ventilation using a smaller volume of the hydraulic circuit filled with expensive respiratory fluid,” said Sergei Dmitrochenko, Deputy General Director of Shvabe.
Development work has made it possible to implement a number of original technical solutions that ensure patient safety in terms of preventing baro- and volutrauma. The GZhIVL device is planned to be used, among other things, for controlled hypothermia — cooling patients down to 30°C in order to reduce the effects of hypoxia that occurs during difficult labor.